Description

5-Fluoro-7-Nitro-Indoline is a high-purity, synthetically versatile heterocyclic building block. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive indoline scaffold.
• Chemical Biology Probe: Serves as a building block for creating fluorescent tags, enzyme inhibitors, and other molecular probes for biological research.
• Material Science: Potential monomer or precursor for the synthesis of specialized polymers and organic electronic materials.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in university and CRO laboratories.
• Custom Synthesis: A starting point for the contract manufacturing of proprietary compounds and fine chemicals.

Basic Information

Product Name	5-Fluoro-7-Nitro-Indoline
CAS No.	2306278-45-3
Molecular Formula	C8H7FN2O2
Molecular Weight	182.15 g/mol
Synonyms	7-Nitro-5-fluoroindoline; 5-Fluoro-7-nitro-2,3-dihydro-1H-indole; 1H-Indole, 5-fluoro-2,3-dihydro-7-nitro-; Indoline, 5-fluoro-7-nitro-; 2306278-45-3; 5-Fluoro-7-nitroindoline; 7-Nitro-5-fluoro-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-7-Nitro-Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.