Description

1H-Indole-1,2-Dicarboxylic Acid, 5-Fluoro-2,3-Dihydro-, 1-(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole core and fluoro-substituted dihydro structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation drugs, including central nervous system (CNS) agents and oncology treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel indole-based heterocyclic compounds.
• Agrochemical Development: Serves as a precursor in the research and development of new generation fluorinated pesticides and herbicides.
• Material Science: Investigated for the creation of specialized organic electronic materials and fluorescent dyes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and process development projects.

Basic Information

Item	Details
Product Name	1H-Indole-1,2-Dicarboxylic Acid, 5-Fluoro-2,3-Dihydro-, 1-(1,1-Dimethylethyl) Ester
CAS No.	2306260-73-9
Molecular Formula	C15H16FNO4
Molecular Weight	293.29 g/mol
Synonyms	5-Fluoro-2,3-dihydro-1H-indole-1,2-dicarboxylic acid 1-tert-butyl ester; tert-Butyl 5-fluoro-2,3-dihydro-1H-indole-1,2-dicarboxylate; 1-tert-Butyl 5-fluoro-2,3-dihydro-1H-indole-1,2-dicarboxylate; 5-Fluoro-2,3-dihydroindole-1,2-dicarboxylic acid 1-(1,1-dimethylethyl) ester; CAS 2306260-73-9; 1-(tert-Butoxycarbonyl)-5-fluoro-2,3-dihydro-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1,2-Dicarboxylic Acid, 5-Fluoro-2,3-Dihydro-, 1-(1,1-Dimethylethyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, GC, NMR, and MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.