Description

1-Isobutyl-3-(Trifluoromethyl)Pyrazole-5-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing pyrazole and trifluoromethyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and liquid crystals.
• Chemical Biology & Medicinal Chemistry: Enables the construction of diverse compound libraries for high-throughput screening and drug discovery programs.
• Catalyst & Ligand Development: Employed in the synthesis of novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Isobutyl-3-(Trifluoromethyl)Pyrazole-5-Boronic Acid
CAS No.	2304633-89-2
Molecular Formula	C8H12BF3N2O2
Molecular Weight	236.00 g/mol
Synonyms	1-Isobutyl-3-(trifluoromethyl)-1H-pyrazole-5-boronic acid; 5-Borono-1-isobutyl-3-(trifluoromethyl)pyrazole; 1H-Pyrazole-5-boronic acid, 1-(2-methylpropyl)-3-(trifluoromethyl)-; (1-Isobutyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)boronic acid; 2304633-89-2; 1-(2-Methylpropyl)-3-(trifluoromethyl)-1H-pyrazole-5-boronic acid
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-3-(Trifluoromethyl)Pyrazole-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.