Description

Methyl 3-(Iodomethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate is a highly functionalized, strained bicyclic building block of significant interest in modern organic synthesis. Its value lies in the unique reactivity imparted by the [1.1.1]propellane core and the versatile iodo-methyl handle, enabling efficient cross-coupling and radical chemistry. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex, three-dimensional molecular architectures and exploring novel chemical space.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing bioisosteres, particularly as a rigid, sp3-rich scaffold to replace aromatic rings or linear chains in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients that require unique steric and electronic properties.
• Materials Science Research: Serves as a monomer or cross-linking agent for developing polymers with tailored mechanical properties and high thermal stability.
• Chemical Biology Probe Development: Employed to create molecular tools and probes for studying biological systems, leveraging its ability to be further functionalized.
• Methodology Development in Organic Chemistry: A valuable substrate for developing new synthetic methodologies involving radical reactions, transition-metal catalysis, and strain-release functionalization.
• Ligand and Catalyst Synthesis: Used to construct sophisticated, three-dimensional ligand frameworks for asymmetric catalysis.

Basic Information

Product Name	Methyl 3-(Iodomethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate
CAS No.	2288708-53-0
Molecular Formula	C9H13IO2
Molecular Weight	280.10 g/mol
Synonyms	Methyl 3-(iodomethyl)bicyclo[1.1.1]pentane-1-carboxylate; 1-(Iodomethyl)-3-(methoxycarbonyl)bicyclo[1.1.1]pentane; Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-(iodomethyl)-, methyl ester; Methyl 3-(iodomethyl)[1.1.1]propellane-1-carboxylate; [1.1.1]Propellane, 3-(iodomethyl)-1-carbomethoxy-; BCP-Iodomethyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(Iodomethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and development documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.