Description

Sitosterol-25,26,26,26,27,27,27-D7 is a high-purity, deuterium-labeled analog of β-sitosterol, a key plant sterol. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily required by pharmaceutical, nutraceutical, and academic research laboratories for pharmacokinetic studies, metabolic research, and the quality control of sterol-based products.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of β-sitosterol and related phytosterols in complex biological matrices like plasma, serum, and tissues.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of plant sterols.
• Nutraceutical and Food Analysis: Enables accurate measurement of sterol content and authenticity testing in functional foods, dietary supplements, and edible oils.
• Biochemical Research: Serves as a tracer in studies of cholesterol metabolism, lipid biosynthesis pathways, and membrane biology.
• Pharmaceutical Development: Supports the bioanalytical method development and validation for sterol-based drug candidates.
• Clinical Diagnostics: Facilitates the reliable measurement of phytosterol levels in clinical samples for research into conditions like sitosterolemia.

Basic Information

Item	Detail
Product Name	Sitosterol-25,26,26,26,27,27,27-D7
CAS No.	2260669-28-9
Molecular Formula	C29H43D7O
Molecular Weight	~ 421.75 g/mol
Synonyms	β-Sitosterol-d7; 24-Ethylcholest-5-en-3β-ol-d7; Stigmast-5-en-3β-ol-d7; (3β)-Stigmast-5-en-3-ol-d7; Phytosterol-d7; Deuterated β-Sitosterol; β-Sitosterol (25,26,26,26,27,27,27-D7); Stable Isotope Labeled Sitosterol
EINECS	Contact for details

Quality Control

Our deuterium-labeled Sitosterol is manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity, which is critical for its role as an analytical standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % D), chemical purity by HPLC, and confirmation of structure by NMR and MS. We adhere to relevant standards for stable isotope-labeled compounds used in regulated bioanalysis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storing desiccated at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0% (by NMR)
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.