Description

1H-Indole-6-Carboxamide, 1-[(2-Chloro-6-Fluorophenyl)Methyl]-2,3-Dihydro-3,3-Dimethyl-2-Oxo-n-[(2,4,6-Trifluorophenyl)Methyl]- is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical building block or intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammatory diseases, or oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Biochemical Tool Compound: Potential use in developing probes for studying specific enzyme or receptor interactions in biological systems.
• Custom Synthesis Building Block: Serves as a specialized starting material for contract manufacturing of complex molecules for clinical trials.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	1H-Indole-6-Carboxamide, 1-[(2-Chloro-6-Fluorophenyl)Methyl]-2,3-Dihydro-3,3-Dimethyl-2-Oxo-n-[(2,4,6-Trifluorophenyl)Methyl]-
CAS No.	2259624-71-8
Molecular Formula	C25H20ClF4N2O2
Molecular Weight	488.88 g/mol
Synonyms	1-[(2-Chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide; 1-[(2-Chloro-6-fluorobenzyl)]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorobenzyl)]-2,3-dihydro-1H-indole-6-carboxamide; 2259624-71-8; UNII-7K8J1C2K8F; 7K8J1C2K8F; Indole-6-carboxamide derivative (based on CAS structure).
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the stringent requirements of GMP-grade manufacturing for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.