Description

1-Chloro-2,3-Bis(Methyl-D3)Benzene is a deuterated aromatic compound where three hydrogen atoms in the methyl groups are replaced by deuterium, a stable isotope of hydrogen. This deuteration is critical for applications requiring enhanced molecular stability, reduced metabolic interference, or as a non-radioactive isotopic tracer. It serves as a valuable building block and internal standard in advanced research and development, particularly within the pharmaceutical and agrochemical sectors. This high-purity specialty chemical is essential for scientists and manufacturers focused on drug discovery, metabolic studies, and analytical method development.

Application

• Pharmaceutical Research & Development: Used as a deuterated intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for improved pharmacokinetic profiles.
• Analytical Chemistry & Mass Spectrometry: Serves as a stable isotope-labeled internal standard for the precise quantification of its non-deuterated analogs in complex matrices via GC-MS or LC-MS.
• Metabolic Pathway Studies: Acts as a non-radioactive tracer to investigate drug metabolism, degradation pathways, and environmental fate studies.
• Agrochemical Development: Employed in the synthesis of deuterated pesticides or herbicides to study their efficacy and environmental persistence.
• Material Science Research: Utilized in the development of specialty polymers or organic electronic materials where isotopic labeling is required to study structure-property relationships.
• NMR Spectroscopy: Functions as a useful probe or solvent additive in nuclear magnetic resonance studies due to its distinct spectroscopic signature.

Basic Information

Product Name	1-Chloro-2,3-Bis(Methyl-D3)Benzene
CAS No.	2256708-72-0
Molecular Formula	C8H4D6Cl
Molecular Weight	159.66 g/mol (approx.)
Synonyms	2,3-Bis(trideuteriomethyl)-1-chlorobenzene; 1-Chloro-2,3-bis(trideuteriomethyl)benzene; 2,3-Bis(methyl-d3)-1-chlorobenzene; (2,3-Bis(trideuteriomethyl)phenyl) chloride; Deuterated 2,3-Dimethylchlorobenzene; Chloro-2,3-bis(methyl-d3)benzene; 1-Chloro-2,3-dimethyl-d6-benzene
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-2,3-Bis(Methyl-D3)Benzene is manufactured and tested under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our standard grade typically meets a deuterium enrichment of ≥98 atom % D and a chemical purity of ≥97% (by GC). Quality is verified through a battery of analytical techniques including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical assay, and impurity profile is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under optimal conditions, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Non-deuterated Impurity (GC-MS)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.