Description

(1R)-1-(Thiophen-2-Yl)Ethan-1-Amine Hcl CAS NO 2252246-01-6 is a chiral amine derivative, specifically the hydrochloride salt of a thiophene-containing primary amine. This compound is a high-value chiral building block critical for the synthesis of enantiomerically pure pharmaceuticals and advanced agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel active pharmaceutical ingredients (APIs), ligands for asymmetric catalysis, and other fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of enantiopure pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or organocatalysts used in stereoselective synthetic transformations.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in organic synthesis and medicinal chemistry.
• Material Science: Potential building block for functionalized polymers or advanced materials with specific electronic properties derived from the thiophene moiety.

Basic Information

Product Name	(1R)-1-(Thiophen-2-Yl)Ethan-1-Amine Hydrochloride
CAS No.	2252246-01-6
Molecular Formula	C6H10ClNS
Molecular Weight	163.67 g/mol
Synonyms	(1R)-1-(2-Thienyl)ethylamine hydrochloride; (R)-1-(Thiophen-2-yl)ethan-1-amine hydrochloride; (R)-α-Methyl-2-thiophenemethylamine hydrochloride; (R)-1-(2-Thienyl)ethylamine HCl; (R)-2-(1-Aminoethyl)thiophene hydrochloride; Dextrorotatory 1-(2-thienyl)ethylamine hydrochloride; (R)-TEA HCl
EINECS	Contact for details

Quality Control

Every batch of (1R)-1-(Thiophen-2-Yl)Ethan-1-Amine HCl is produced under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Our quality assurance protocol is designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing chiral purity (by chiral HPLC), assay, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.