Description

Propargyl-Peg3-Triethoxysilane is a specialized bifunctional organosilane coupling agent that combines a reactive propargyl group with a triethoxysilane anchor via a polyethylene glycol (PEG) spacer. This unique molecular architecture is critical for creating stable, functionalized interfaces between inorganic substrates and organic polymers or biomolecules. It is essential for researchers and manufacturers in advanced materials science who require precise surface modification and controlled covalent attachment. Key industries leveraging this compound include pharmaceuticals for bioconjugation, electronics for thin-film coatings, and nanotechnology for sensor development.

Application

• Surface Functionalization: Covalent modification of glass, silicon, metal oxides, and nanoparticles to introduce alkyne groups for subsequent "click chemistry" reactions.
• Bioconjugation & Drug Delivery: Serving as a heterobifunctional linker for attaching drugs, peptides, or fluorescent dyes to carrier systems or solid supports via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Hydrophilic Coatings & Adhesion Promotion: Improving the adhesion and wettability of coatings, inks, and adhesives on challenging substrates due to the hydrophilic PEG spacer and reactive silane.
• Polymer & Composite Modification: Incorporation into polymer matrices or nanocomposites as a crosslinking agent or to enhance filler-matrix compatibility.
• Sensor & Diagnostic Device Fabrication: Immobilization of biorecognition elements (e.g., antibodies, DNA) onto transducer surfaces for biosensor applications.
• Chromatography & Solid-Phase Synthesis: Functionalization of silica gels and other stationary phases for affinity chromatography or combinatorial chemistry.

Basic Information

Product Name	Propargyl-Peg3-Triethoxysilane
CAS No.	2250216-92-1
Molecular Formula	C16H32O6Si
Molecular Weight	348.52 g/mol
Synonyms	3-(2-(2-(2-Prop-2-yn-1-yloxy)ethoxy)ethoxy)propyltriethoxysilane; Propargyl-PEG3-triethoxysilane; Propargyl-PEG3-triethoxysilane; Alkyne-PEG3-triethoxysilane; 2,5,8,11-Tetraoxatetradec-13-yn-14-yltriethoxysilane; Triethoxy(3-(2-(2-(2-prop-2-yn-1-yloxy)ethoxy)ethoxy)propyl)silane; Propargyloxy-PEG3-triethoxysilane; Click Chemistry Silane Reagent
EINECS	Contact for details

Quality Control

Every batch of Propargyl-Peg3-Triethoxysilane is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and performance consistency. Our quality system is designed to meet the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by NMR and HPLC), identity confirmation, and other critical parameters is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
NMR Analysis	Conforms (1H NMR, 13C NMR)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.