Description

4,4,5,5-Tetramethyl-2-(3-((o-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures essential for pharmaceutical and materials science research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science & OLED Development: Building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and other advanced organic electronic components.
• Chemical Research & Process Development: Essential reagent in academic and industrial laboratories for method development and scaling up synthetic routes.
• Ligand & Catalyst Synthesis: Serves as a starting material for the preparation of specialized ligands and organometallic catalysts.
• Polymer Chemistry: Can be incorporated into polymer backbones to modify physical properties and introduce functional handles for further modification.

Basic Information

Item	Details
Product Name	4,4,5,5-Tetramethyl-2-(3-((o-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	2246632-59-5
Molecular Formula	C20H25BO3
Molecular Weight	324.22 g/mol
Synonyms	2-(3-((2-Methylphenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-((o-Tolyloxy)methyl)phenylboronic acid pinacol ester; (3-((2-Methylphenoxy)methyl)phenyl)boronic acid pinacol ester; 2-Methylphenyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl ether; B-(3-((2-Methylphenoxy)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(3-((o-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical R&D and other high-value chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.