Description

8-Chloro-7-Fluoro-6-Iodoisoquinolin-3-Amine is a high-purity, multi-halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique halogen substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the development of novel molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by leveraging its halogenated scaffold.
• Material Science: Serves as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Catalyst Ligand Synthesis: The amine and halogen groups allow for the creation of novel ligands for transition metal catalysis.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Item	Details
Product Name	8-Chloro-7-Fluoro-6-Iodoisoquinolin-3-Amine
CAS No.	2246363-09-5
Molecular Formula	C9H5ClFIN2
Molecular Weight	337.50 g/mol
Synonyms	8-Chloro-7-fluoro-6-iodo-3-isoquinolinamine; 3-Amino-8-chloro-7-fluoro-6-iodoisoquinoline; 8-Chloro-7-fluoro-6-iodoisoquinolin-3-ylamine; 2246363-09-5; 8-Cl-7-F-6-I-isoquinolin-3-NH2; 3-Isoquinolinamine, 8-chloro-7-fluoro-6-iodo-; C9H5ClFIN2
EINECS	Contact for details

Quality Control

Our 8-Chloro-7-Fluoro-6-Iodoisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.