Description

1-(4-Bromothiophen-2-Yl)Ethan-1-Amine Hydrochloride is a high-purity organic building block featuring a brominated thiophene core, a valuable scaffold in modern synthetic chemistry. This compound is essential for researchers and manufacturers requiring a versatile amine intermediate with a halogen handle for further functionalization. It is primarily utilized in the development of novel pharmaceuticals, agrochemicals, and advanced materials, serving as a critical precursor for coupling reactions and molecular diversification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and liquid crystals.
• Chemical Synthesis: Acts as a versatile precursor for Suzuki, Sonogashira, and Buchwald-Hartwig cross-coupling reactions due to the reactive bromine substituent.
• Bioconjugation & Probe Development: Useful for labeling and modifying biomolecules in diagnostic and biochemical research applications.

Basic Information

Product Name	1-(4-Bromothiophen-2-Yl)Ethan-1-Amine Hydrochloride
CAS No.	2244906-14-5
Molecular Formula	C6H7BrClNS
Molecular Weight	240.55 g/mol
Synonyms	1-(4-Bromo-2-thienyl)ethanamine hydrochloride; 1-(4-Bromothiophen-2-yl)ethanamine HCl; 4-Bromo-2-(1-aminoethyl)thiophene hydrochloride; 2-(4-Bromothiophen-2-yl)ethanamine hydrochloride; α-Amino-4-bromothiophene-2-ethane hydrochloride; (4-Bromo-2-thienyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromothiophen-2-Yl)Ethan-1-Amine Hydrochloride adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.