Description

(3-Fluorophenyl)Boronic Acid-D4 is a deuterated derivative of (3-fluorophenyl)boronic acid, a valuable organoboron building block. This isotopically labeled compound is essential for applications requiring high sensitivity and specificity, such as in mass spectrometry and metabolic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery, development of Suzuki-Miyaura coupling reactions, and as a tracer in analytical chemistry.

Application

• Pharmaceutical Research & Development: As a deuterated intermediate in the synthesis of isotopically labeled drug candidates for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry Standard: Serves as an internal standard or reference material in quantitative mass spectrometry (LC-MS/MS, GC-MS) for accurate bioanalysis and metabolite identification.
• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for creating carbon-carbon bonds in the synthesis of complex, fluorinated biaryl structures for advanced materials and fine chemicals.
• Agrochemical Development: Used in the research and synthesis of novel, labeled active ingredients or their metabolites for environmental fate and residue analysis.
• Isotope Labeling & Tracing: Enables mechanistic studies and pathway elucidation in chemical and biochemical processes due to its deuterium atoms.
• Material Science: Potential building block for creating deuterated polymers or organic electronic materials with modified physical properties.

Basic Information

Product Name	(3-Fluorophenyl)Boronic Acid-D4
CAS No.	2241870-71-1
Molecular Formula	C6H2D4BF1O2
Molecular Weight	143.96 g/mol (approx.)
Synonyms	(3-Fluorophenyl)boronic-2,3,5,6-d4 acid; (3-Fluorophenyl-d4)boronic Acid; 3-Fluorobenzeneboronic Acid-d4; m-Fluorophenylboronic Acid-d4; B-(3-Fluorophenyl-d4)boronic Acid; (3-Fluorophenyl)boronic Acid (phenyl-d4); Deuterated (3-Fluorophenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our (3-Fluorophenyl)Boronic Acid-D4 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (1H, 11B, 19F), HPLC/LC-MS for chemical purity and isotopic enrichment (D-content), and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/Certificate of Analysis. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) in a sealed container to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.