Description

(5-(Methoxy-D3)Pyridin-3-Yl)Boronic Acid CAS NO 2241867-27-4 is a deuterated boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the precise construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of deuterated active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing deuterated drug candidates, leveraging the kinetic isotope effect to potentially improve metabolic stability and pharmacokinetic profiles.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile organoboron reagent for forming carbon-carbon bonds between pyridine derivatives and various aryl/vinyl halides.
• Agrochemical Research: Employed in the discovery and development of novel, labeled pesticides and herbicides with enhanced properties.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Isotope Labeling Studies: Utilized in metabolic and mechanistic studies (e.g., Mass Spectrometry, NMR) as a stable isotope-labeled probe.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of activity-based probes and inhibitors.

Basic Information

Item	Details
Product Name	(5-(Methoxy-D3)Pyridin-3-Yl)Boronic Acid
CAS No.	2241867-27-4
Molecular Formula	C6H6D3BNO3
Molecular Weight	154.96 g/mol
Synonyms	(5-(Trideuteriomethoxy)pyridin-3-yl)boronic acid; 3-Pyridineboronic acid, 5-(methoxy-d3)-; 5-(Methoxy-d3)-3-pyridinylboronic Acid; (5-(Methoxy-d3)-3-pyridyl)boronic Acid; Deuterated (5-Methoxypyridin-3-yl)boronic Acid; Boronic acid, B-[5-(methoxy-d3)-3-pyridinyl]-; Deuterated Pyridinyl Boronic Acid Ester Precursor
EINECS	Contact for details

Quality Control

Our (5-(Methoxy-D3)Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and mass spectrometry, to ensure high chemical purity, isotopic enrichment, and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.