Description

1H-Indazole, 4-Bromo-6-Fluoro-5-Methyl- is a high-purity, multi-halogenated indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their R&D and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the indazole core for biological activity.
• Material Science Research: Acts as a precursor for the synthesis of specialized organic ligands, dyes, and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Academic & Industrial R&D: Serves as a versatile scaffold in medicinal chemistry and process chemistry research within university and corporate laboratories.
• Custom Synthesis Building Block: Provides a halogenated, functionalized starting point for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	1H-Indazole, 4-Bromo-6-Fluoro-5-Methyl-
CAS No.	2241720-66-9
Molecular Formula	C8H6BrFN2
Molecular Weight	229.05 g/mol
Synonyms	4-Bromo-6-fluoro-5-methyl-1H-indazole; 4-Bromo-6-fluoro-5-methylindazole; 5-Methyl-4-bromo-6-fluoroindazole; 6-Fluoro-5-methyl-4-bromo-1H-indazole; 1H-Indazole, 4-bromo-6-fluoro-5-methyl-; 2241720-66-9; 4-Bromo-6-fluoro-5-methylindazole; 4-Bromo-6-fluoro-5-methyl-1H-indazole
EINECS	Contact for details

Quality Control

Every batch of 1H-Indazole, 4-Bromo-6-Fluoro-5-Methyl- undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to support cGMP and ISO compliant workflows. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.