Description

Methanone, [4-[(3-Fluorophenyl)Methoxy]-3-Methoxyphenyl][4-[1-[(3-Fluorophenyl)Methyl]-1H-Benzimidazol-2-Yl]-1-Piperidinyl]- is a high-purity, non-racemic chiral compound designed for advanced research and development. This molecule is of significant interest due to its complex structure, which incorporates benzimidazole and piperidine moieties, making it a valuable pharmaceutical intermediate or biological research probe. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents, particularly in areas targeting specific enzyme or receptor pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for potential candidates in oncology or central nervous system (CNS) disorders.
• Biochemical Research: Used as a reference standard or a tool compound in high-throughput screening (HTS) and structure-activity relationship (SAR) studies to investigate biological activity.
• Medicinal Chemistry: Provides a sophisticated scaffold for medicinal chemists to explore and optimize drug-like properties, including potency, selectivity, and metabolic stability.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis, asymmetric catalysis, and molecular recognition.
• Process Development: Acts as a critical material for scaling up synthetic routes and developing robust, GMP-compliant manufacturing processes for clinical trial materials.

Basic Information

Product Name	Methanone, [4-[(3-Fluorophenyl)Methoxy]-3-Methoxyphenyl][4-[1-[(3-Fluorophenyl)Methyl]-1H-Benzimidazol-2-Yl]-1-Piperidinyl]-
CAS No.	2241651-99-8
Molecular Formula	C34H31F2N3O3
Molecular Weight	567.63 g/mol
Synonyms	[4-[(3-Fluorophenyl)Methoxy]-3-Methoxyphenyl][4-[1-[(3-Fluorophenyl)Methyl]-1H-Benzimidazol-2-Yl]-1-Piperidinyl]methanone; (4-((3-Fluorobenzyl)oxy)-3-methoxyphenyl)(4-(1-((3-fluorophenyl)methyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)methanone; CAS 2241651-99-8; Benzimidazole-piperidine methanone derivative; Fluorinated benzimidazole intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support development from research to commercial scale with cGMP-compliant documentation and practices upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.