Description

n-Acetyl-L-Alanine-2,3,3,3-D4 is a deuterium-labeled derivative of the amino acid alanine, specifically designed for advanced research and analytical applications. This stable isotope-labeled compound is essential for use as an internal standard in mass spectrometry, enabling highly accurate quantification and metabolic pathway tracing in complex biological matrices. It is primarily utilized by researchers and scientists in the fields of pharmaceutical development, metabolomics, proteomics, and clinical diagnostics where precise measurement is critical.

Application

• Mass Spectrometry Internal Standard: Used for the accurate quantification of L-alanine and related metabolites in LC-MS/MS and GC-MS analyses.
• Metabolic Pathway Research: Aids in tracing and studying amino acid metabolism, protein synthesis, and energy production pathways in biological systems.
• Pharmaceutical R&D: Employed in drug metabolism and pharmacokinetics (DMPK) studies to understand the fate of new chemical entities.
• Clinical Diagnostics: Serves as a critical component in developing high-precision assays for detecting metabolic disorders.
• Biomarker Discovery: Facilitates the identification and validation of disease biomarkers in metabolomic profiling studies.
• Nutritional Science Research: Used in studies investigating protein metabolism, muscle synthesis, and dietary impacts.

Basic Information

Item	Detail
Product Name	n-Acetyl-L-Alanine-2,3,3,3-D4
CAS No.	2230887-18-8
Molecular Formula	C5H5D4NO3
Molecular Weight	135.15 g/mol (approx.)
Synonyms	N-Acetyl-L-alanine-2,3,3,3-d4; (2S)-2-Acetamidopropanoic-2,3,3,3-d4 Acid; Ac-Ala(D4)-OH; L-Alanine, N-acetyl-, 2,3,3,3-d4; Deuterated N-Acetyl-L-alanine; N-Acetylalanine-d4; Stable Isotope Labeled N-Acetylalanine; Internal Standard for Alanine Analysis
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-L-Alanine-2,3,3,3-D4 is produced and tested under stringent quality protocols to ensure the highest standards of isotopic purity and chemical integrity. Our quality assurance includes comprehensive analysis via NMR, HPLC, and mass spectrometry to confirm isotopic enrichment and chemical purity. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.