Description

Methyl 3-Bromo-5-Fluoro-1H-Indole-6-Carboxylate is a high-value, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored biological and chemical properties. This compound is primarily sought after by pharmaceutical research and development teams, agrochemical innovators, and specialty chemical manufacturers for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools for biological study.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and CRO/CMO settings.
• Custom Synthesis: A versatile starting point for the custom manufacturing of complex, halogenated heterocyclic compounds.

Basic Information

Product Name	Methyl 3-Bromo-5-Fluoro-1H-Indole-6-Carboxylate
CAS No.	2227205-24-3
Molecular Formula	C10H7BrFNO2
Molecular Weight	272.07 g/mol
Synonyms	Methyl 3-bromo-5-fluoro-1H-indole-6-carboxylate; 3-Bromo-5-fluoro-1H-indole-6-carboxylic acid methyl ester; 6-Carbomethoxy-3-bromo-5-fluoroindole; 1H-Indole-6-carboxylic acid, 3-bromo-5-fluoro-, methyl ester; Methyl 3-bromo-5-fluoroindole-6-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-5-Fluoro-1H-Indole-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.