Description

6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically valuable organic salt primarily utilized as a key building block in advanced pharmaceutical research and development. Its core value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are crucial scaffolds in modern medicinal chemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the exploration of new bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides that require complex heterocyclic structures.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and the production of non-commercially available fine chemicals.

Basic Information

Product Name	6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	2227205-04-9
Molecular Formula	C10H13BrClN
Molecular Weight	262.57 g/mol
Synonyms	6-Bromo-4-methyl-1,2,3,4-tetrahydroisoquinoline HCl; 4-Methyl-6-bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6-bromo-4-methylisoquinoline hydrochloride; 6-Bromo-4-methyl-3,4-dihydro-1H-isoquinoline hydrochloride; 2227205-04-9; 6-Br-4-Me-THIQ·HCl
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.