Description

5-Bromo-6-Fluoroisoquinolin-3-Amine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated isoquinoline scaffold, which provides a versatile platform for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in medicinal chemistry, drug discovery, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a building block for creating specialized organic ligands, dyes, and functional polymers.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable amine and halogen groups.
• Chemical Biology: Utilized as a probe or tag in biochemical assays and for the development of molecular imaging agents.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and exploratory research in organic chemistry.

Basic Information

Product Name	5-Bromo-6-Fluoroisoquinolin-3-Amine
CAS No.	2225879-49-0
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	5-Bromo-6-fluoroisoquinolin-3-amine; 3-Amino-5-bromo-6-fluoroisoquinoline; 5-Bromo-6-fluoro-3-isoquinolinamine; 6-Fluoro-5-bromoisoquinolin-3-amine; Isoquinolin-3-amine, 5-bromo-6-fluoro-; 2225879-49-0; 5-Br-6-F-IQ-3-NH2
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoroisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance with the standards required for research and cGMP-grade pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.