Description

1-Isoquinolinecarboxylic Acid, 4-Fluoro- is a high-value fluorinated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom, which can significantly alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the fluorine moiety enhances bioactivity and environmental stability.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Acts as a versatile probe or labeling agent in biochemical research due to its unique fluorinated aromatic structure.
• Academic & R&D: Serves as a fundamental reagent in university and corporate laboratories for methodological studies in fluorination and heterocyclic chemistry.

Basic Information

Product Name	1-Isoquinolinecarboxylic Acid, 4-Fluoro-
CAS No.	2225878-70-4
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	4-Fluoro-1-isoquinolinecarboxylic acid; 4-Fluoro-isoquinoline-1-carboxylic acid; 4-Fluoro-1-carboxyisoquinoline; 1-Carboxy-4-fluoroisoquinoline; 4-Fluoroisoquinoline-1-carboxylic acid; 1-Isoquinolinecarboxylic acid, 4-fluoro-; 4-Fluoro-1-isoquinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 1-Isoquinolinecarboxylic Acid, 4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.