Description

2-(4-Cyclopropyl-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile and stable intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aryl-aryl bonds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl motifs for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Fine Chemical Production: An important reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic compounds on scale.

Basic Information

Product Name	2-(4-Cyclopropyl-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2223040-90-0
Molecular Formula	C16H23BO2
Molecular Weight	258.17 g/mol
Synonyms	4-Cyclopropyl-2-methylbenzeneboronic acid pinacol ester; (4-Cyclopropyl-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-4-cyclopropylphenylboronic acid pinacol ester; Pinacol (4-cyclopropyl-2-methylphenyl)boronate; 4-Cyclopropyl-2-methylphenyl-Bpin; B-(4-Cyclopropyl-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Cyclopropyl-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards in GMP-compliant or research-grade environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity during use. Ideal storage temperature is between 2°C and 8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.