Description

4,4,5,5-Tetramethyl-2-(3-(Tetrahydrofuran-3-Yl)Phenyl)-1,3,2-Dioxaborolane is a high-value, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of complex aromatic and heterocyclic structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating sophisticated organic semiconductors and emissive layer materials in display and lighting technologies.
• Polymer & Material Science: Employed in the synthesis of functional polymers, liquid crystals, and advanced organic frameworks with tailored electronic or mechanical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex boronic acid derivatives.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(3-(Tetrahydrofuran-3-Yl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	2223005-33-0
Molecular Formula	C16H23BO3
Molecular Weight	274.17 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyltetrahydrofuran-3-yl; 2-[3-(Oxolan-3-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Tetrahydrofuran-3-yl)phenylboronic acid pinacol ester; (3-(Tetrahydrofuran-3-yl)phenyl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-tetrahydrofuran-3-ylbenzene; Boronic acid, B-[3-(tetrahydro-3-furanyl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(3-(Tetrahydrofuran-3-Yl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (1H and 13C), and GC-MS, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.