Description

(R)-1-(1H-Indazol-4-Yl)Propan-2-Amine Dihydrochloride is a high-purity chiral amine derivative, specifically the dihydrochloride salt of an indazole-containing compound. This product is a critical building block in modern pharmaceutical research and development, offering a defined stereochemistry essential for creating targeted bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates, particularly in areas requiring specific receptor interaction.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and commercial route development for potential therapeutics.
• Biochemical Tool Compound: Potential use in the development of enzyme inhibitors or receptor ligands for biological research.
• Asymmetric Synthesis: Employed in the synthesis of complex molecules where the (R)-configuration of the amine center is crucial for biological activity.

Basic Information

Product Name	(R)-1-(1H-Indazol-4-Yl)Propan-2-Amine Dihydrochloride
CAS No.	2222846-05-9
Molecular Formula	C₁₀H₁₅Cl₂N₃
Molecular Weight	248.15 g/mol
Synonyms	(R)-1-(1H-Indazol-4-yl)propan-2-amine dihydrochloride; (R)-1-(1H-Indazol-4-yl)-2-propylamine dihydrochloride; (R)-4-(1-Amino-2-propyl)-1H-indazole dihydrochloride; (R)-1-(1H-Indazol-4-yl)propan-2-amine hydrochloride (1:2); UNII-9F8F0Y1K8I; (R)-1-(1H-Indazol-4-yl)-2-aminopropane dihydrochloride; (R)-α-Methyl-1H-indazole-4-ethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(1H-Indazol-4-Yl)Propan-2-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as chiral purity, assay, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.