Description

2,6-Piperidinedione, 3-(1,3-Dihydro-4-Iodo-1-Oxo-2H-Isoindol-2-Yl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating an isoindole moiety. This compound is of significant value in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, especially those targeting neurological or oncological pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and studying structure-activity relationships (SAR).
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing processes under GMP conditions.
• Bioconjugation & Probe Development: Potential utility in creating labeled compounds or molecular probes for biochemical and diagnostic research due to its reactive sites.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2,6-Piperidinedione, 3-(1,3-Dihydro-4-Iodo-1-Oxo-2H-Isoindol-2-Yl)-
CAS No.	2207541-30-6
Molecular Formula	C13H10IN2O3
Molecular Weight	369.14 g/mol
Synonyms	3-(4-Iodo-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; 3-(1,3-Dihydro-4-iodo-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 4-Iodo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; Iodinated Glutarimide Isoindole Derivative; Advanced Pharmaceutical Intermediate 2207541-30-6
EINECS	Contact for details

Quality Control

Our production of 2,6-Piperidinedione, 3-(1,3-Dihydro-4-Iodo-1-Oxo-2H-Isoindol-2-Yl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.