Description

4-Bromo-5,6-Dimethyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate designed for specialized synthesis. This compound matters because it serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• API Development: Serves as a building block for constructing complex heterocyclic cores in active pharmaceutical ingredient (API) manufacturing.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-Bromo-5,6-Dimethyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole
CAS No.	2206742-48-3
Molecular Formula	C₁₄H₁₇BrN₂O
Molecular Weight	309.20 g/mol
Synonyms	4-Bromo-5,6-dimethyl-1-(oxan-2-yl)-1H-indazole; 4-Bromo-5,6-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1H-Indazole, 4-bromo-5,6-dimethyl-1-(tetrahydro-2H-pyran-2-yl)-; 4-Bromo-5,6-dimethyl-1-(tetrahydropyran-2-yl)-1H-indazole; THP-protected 4-bromo-5,6-dimethylindazole; 4-Br-5,6-diMe-1-THP-indazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,6-Dimethyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.