Description

Ethyl 1-({[2-(Methoxycarbonyl)-4-Methylthien-3-Yl]Amino}Carbonothioyl)Piperidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block with defined stereochemistry and functional groups essential for modern drug discovery and development processes. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in creating novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic and peptidomimetic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly for targeted therapies.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial labs.
• API Synthesis: Serves as a crucial building block in the production route of complex Active Pharmaceutical Ingredients (APIs).
• Peptidomimetic Chemistry: The piperidine-3-carboxylate core makes it valuable for designing molecules that mimic peptide structures with improved metabolic stability.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Biology Probes: Potential use in the development of specialized probes for studying biological pathways and target engagement.

Basic Information

Product Name	Ethyl 1-({[2-(Methoxycarbonyl)-4-Methylthien-3-Yl]Amino}Carbonothioyl)Piperidine-3-Carboxylate
CAS No.	2197063-00-4
Molecular Formula	C16H21N3O4S2
Molecular Weight	383.48 g/mol
Synonyms	Ethyl 1-({[2-(Methoxycarbonyl)-4-methylthiophen-3-yl]amino}carbonothioyl)piperidine-3-carboxylate; 1-({[2-(Methoxycarbonyl)-4-Methylthien-3-Yl]Amino}Carbonothioyl)Piperidine-3-Carboxylic Acid Ethyl Ester; 3-Carbethoxy-1-[(2-methoxycarbonyl-4-methyl-3-thienyl)thiocarbamoyl]piperidine; CAS 2197063-00-4; Advanced Piperidine-Thiophene Intermediate; Pharmaceutical Building Block 2197063-00-4.
EINECS	Contact for details

Quality Control

Our Ethyl 1-({[2-(Methoxycarbonyl)-4-Methylthien-3-Yl]Amino}Carbonothioyl)Piperidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.