Description

6-Chloro-2-(Piperidin-3-Yl)-1H-Benzo[D]Imidazole Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing targeted small molecule libraries and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates targeting specific protein kinases and receptors.
• Oncology Research: Used in the development of potential anti-cancer agents due to the benzimidazole core's known biological activity.
• CNS Drug Discovery: Serves as a scaffold for creating compounds aimed at neurological disorders, leveraging the piperidine moiety.
• Chemical Biology & Proteomics: Employed as a molecular probe or tool compound for studying enzyme function and cellular pathways.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects, from milligram-scale research to kilogram-scale process development.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Chloro-2-(Piperidin-3-Yl)-1H-Benzo[D]Imidazole Hydrochloride
CAS No.	2197053-85-1
Molecular Formula	C12H15ClN3·HCl
Molecular Weight	274.63 g/mol (Free base: 238.72 g/mol)
Synonyms	6-Chloro-2-(3-piperidinyl)-1H-benzimidazole hydrochloride; 6-Chloro-2-(piperidin-3-yl)-1H-benzo[d]imidazole HCl; 1H-Benzimidazole, 6-chloro-2-(3-piperidinyl)-, hydrochloride; 6-Chloro-2-(3-piperidyl)-1H-benzimidazole hydrochloride; 2197053-85-1; 6-Chloro-2-(piperidin-3-yl)-1H-benzoimidazole hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a quality management system suitable for supplying materials for research and development under current Good Manufacturing Practice (cGMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccant and nitrogen purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.