Description

(2-Chlorophenyl)(1-Oxo-1,3-Dihydro-2H-Isoindol-2-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoindolinone core linked to a chlorophenyl acetic acid moiety. This compound matters for its critical role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation therapeutic agents, leveraging its specific structure to impart desired biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel small-molecule drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized as a component in the linker or warhead design for targeted protein degradation therapeutics.
• Kinase Inhibitor Synthesis: Employed in the construction of potential kinase inhibitors due to the pharmacophore-like properties of the isoindolinone scaffold.
• Chemical Biology Research: Acts as a versatile scaffold for creating molecular probes to study enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific API development projects.
• Academic Research: Used in university and institutional labs for medicinal chemistry programs and novel heterocyclic compound exploration.

Basic Information

Product Name	(2-Chlorophenyl)(1-Oxo-1,3-Dihydro-2H-Isoindol-2-Yl)Acetic Acid
CAS No.	2197052-97-2
Molecular Formula	C16H12ClNO3
Molecular Weight	301.72 g/mol
Synonyms	2-[(2-Chlorophenyl)(1-oxo-1,3-dihydro-2H-isoindol-2-yl)]acetic Acid; (2-Chlorophenyl)(1-oxoisoindolin-2-yl)acetic Acid; 2-(2-Chlorophenyl)-2-(1-oxoisoindolin-2-yl)acetic Acid; 2197052-97-2; UNII-Contact for details; Isoindolin-1-one Derivative; Chlorophenyl Isoindolinone Acetic Acid
EINECS	Contact for details

Quality Control

Our (2-Chlorophenyl)(1-Oxo-1,3-Dihydro-2H-Isoindol-2-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.