Description

(3-Ethynyl-4-Fluorophenoxy)(tert-Butyl)Dimethylsilane is a high-value organosilicon building block featuring a protected ethynyl group and a fluorinated aromatic ring. This compound is critical for advanced organic synthesis, particularly in the development of pharmaceuticals and functional materials where precise molecular architecture is required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that require fluorinated aromatic components.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers, resins, and silicon-based hybrid materials.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organometallic chemistry.
• Fluorescent Probe and Dye Synthesis: Acts as a precursor for labeling reagents and fluorophores used in bioimaging and diagnostics.
• Academic and Industrial R&D: Essential reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	(3-Ethynyl-4-Fluorophenoxy)(tert-Butyl)Dimethylsilane
CAS No.	2187435-17-0
Molecular Formula	C14H19FOSi
Molecular Weight	250.38 g/mol
Synonyms	tert-Butyl(3-ethynyl-4-fluorophenoxy)dimethylsilane; (3-Ethynyl-4-fluorophenoxy)dimethyl-tert-butylsilane; 4-Fluoro-3-[(tert-butyldimethylsilyl)oxy]phenylacetylene; 3-[(tert-Butyldimethylsilyl)oxy]-4-fluorophenylacetylene; TBDMS ether of 3-ethynyl-4-fluorophenol
EINECS	Contact for details

Quality Control

Every batch of (3-Ethynyl-4-Fluorophenoxy)(tert-Butyl)Dimethylsilane is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our standard quality commitment includes comprehensive analysis via HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.