Description

4-Isoquinolinecarboxylic Acid, 6-(Trifluoromethyl)- is a high-value trifluoromethyl-substituted isoquinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Building block for developing new pesticides and herbicides, leveraging the biological activity of the trifluoromethyl and isoquinoline motifs.
• Material Science: Used in the creation of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Chemical Synthesis: A versatile scaffold for medicinal chemistry and organic synthesis, enabling structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	4-Isoquinolinecarboxylic Acid, 6-(Trifluoromethyl)-
CAS No.	2177266-08-7
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	6-(Trifluoromethyl)isoquinoline-4-carboxylic acid; 6-Trifluoromethyl-4-isoquinolinecarboxylic Acid; 4-Carboxy-6-trifluoromethylisoquinoline; 6-Trifluoromethylisoquinoline-4-carboxylic Acid; 2177266-08-7; AI3-73487; ZINC000103254507
EINECS	Contact for details

Quality Control

Our 4-Isoquinolinecarboxylic Acid, 6-(Trifluoromethyl)- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.