Description

5-Bromothiophen-3-Amine Hydrobromide is a high-purity organic salt derivative of a brominated thiophene amine, serving as a critical building block in advanced chemical synthesis. This compound is valued for its role in constructing complex heterocyclic scaffolds, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for its precise reactivity and structural utility.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Chemical Synthesis: Acts as a versatile building block for constructing more complex heterocyclic compounds like thienopyrimidines, thienopyridines, and fused ring systems.
• Dye & Pigment Industry: Utilized in the synthesis of specialized dyes and organic pigments due to the electron-rich thiophene core.
• Academic & R&D: Essential for methodological studies and discovery chemistry in university and corporate research laboratories.

Basic Information

Product Name	5-Bromothiophen-3-Amine Hydrobromide
CAS No.	2173992-08-8
Molecular Formula	C4H5Br2NS
Molecular Weight	283.97 g/mol
Synonyms	3-Amino-5-bromothiophene hydrobromide; 5-Bromo-3-thiophenamine hydrobromide; 5-Bromothiophen-3-ylamine hydrobromide; 3-Thiophenamine, 5-bromo-, hydrobromide; 5-Bromo-3-aminothiophene HBr; 5-Bromothiophene-3-amine HBr salt
EINECS	Contact for details

Quality Control

Our 5-Bromothiophen-3-Amine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.