Description

3-Iodo-1H-Indole-7-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines an iodine substituent and a nitrile group on the indole scaffold, enabling precise derivatization and cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the creation of novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a building block for organic semiconductors, dyes, and photoactive materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Functional Group Transformation: The nitrile group can be hydrolyzed to carboxylic acids or reduced to amines, enabling diverse molecular diversification.
• Academic & Contract Research: Essential for methodological studies and library synthesis in university and CRO laboratories.

Basic Information

Product Name	3-Iodo-1H-Indole-7-Carbonitrile
CAS No.	2170826-58-9
Molecular Formula	C9H5IN2
Molecular Weight	268.06 g/mol
Synonyms	7-Cyano-3-iodo-1H-indole; 3-Iodo-1H-indole-7-carbonitrile; 1H-Indole-7-carbonitrile, 3-iodo-; 3-Iodoindole-7-carbonitrile; 3-Iodo-7-cyanoindole
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Indole-7-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.