Description

3-(Bromomethyl)Bicyclo[1.1.1]Pentan-1-Ol is a high-value, strained bicyclic building block featuring a reactive bromomethyl group and a hydroxyl functionality. This unique molecular architecture makes it a critical intermediate for constructing complex three-dimensional frameworks in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for applications in medicinal chemistry, chemical biology, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating sp3-rich, bioisosteric scaffolds that mimic saturated carbon centers.
• Agrochemical Synthesis: Used in the development of new active ingredients with potentially improved efficacy and environmental profiles.
• Chemical Biology Probe Development: Employed to create tool compounds and molecular probes for studying biological pathways and protein-ligand interactions.
• Materials Science Research: Acts as a monomer or cross-linking agent for developing polymers with unique mechanical or optical properties derived from the rigid bicyclo[1.1.1]pentane core.
• Ligand and Catalyst Design: Utilized to synthesize novel chelating ligands or organocatalysts with constrained geometries.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and membrane permeability.

Basic Information

Product Name	3-(Bromomethyl)Bicyclo[1.1.1]Pentan-1-Ol
CAS No.	2169489-80-7
Molecular Formula	C7H11BrO
Molecular Weight	191.07 g/mol
Synonyms	1-Bicyclo[1.1.1]pentan-1-ol, 3-(bromomethyl)-; 3-(Bromomethyl)-1-hydroxybicyclo[1.1.1]pentane; Bicyclo[1.1.1]pentan-1-ol, 3-(bromomethyl)-; 3-(Bromomethyl)bicyclo[1.1.1]pentan-1-ol; BCP-Br-OH
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)Bicyclo[1.1.1]Pentan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch-specific data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.