Description

Methyl 1,2,3,9B-Tetrahydrobenzo[C]Thieno[2,1-E]Isothiazole-8-Carboxylate 4-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new drug candidates with potential therapeutic effects.
• Organic Synthesis: Serves as a sophisticated precursor for constructing complex polycyclic frameworks in academic and industrial research settings.
• Biochemical Research: May be utilized as a tool compound or probe in biochemical assays to investigate specific biological pathways and targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Item	Details
Product Name	Methyl 1,2,3,9B-Tetrahydrobenzo[C]Thieno[2,1-E]Isothiazole-8-Carboxylate 4-Oxide
CAS No.	2169310-99-8
Molecular Formula	C12H11NO3S2
Molecular Weight	281.35 g/mol
Synonyms	Methyl 1,2,3,9b-tetrahydrobenzo[c]thieno[2,1-e]isothiazole-8-carboxylate 4-oxide; Benzo[c]thieno[2,1-e]isothiazole-8-carboxylic acid, 1,2,3,9b-tetrahydro-, methyl ester, 4-oxide; CAS 2169310-99-8; Thienoisothiazole carboxylate derivative; Pharmaceutical intermediate 2169310-99-8
EINECS	Contact for details

Quality Control

Our production of Methyl 1,2,3,9B-Tetrahydrobenzo[C]Thieno[2,1-E]Isothiazole-8-Carboxylate 4-Oxide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades compliant with cGMP guidelines for advanced clinical trials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.