Description

8-Bromo-1,2,3,9B-tetrahydrobenzo[C]thieno[2,1-E]isothiazole 4-oxide is a high-value, specialized heterocyclic compound featuring a fused benzothienoisothiazole core. This molecule is of significant interest as a key synthetic intermediate and a versatile scaffold in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for the development of novel therapeutic agents and crop protection solutions. The compound's unique structure offers multiple sites for further functionalization, enabling the exploration of new chemical space.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Material Science Research: Investigated as a potential monomer or precursor for novel organic electronic materials due to its fused heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	8-Bromo-1,2,3,9B-tetrahydrobenzo[C]thieno[2,1-E]isothiazole 4-oxide
CAS No.	2169310-95-4
Molecular Formula	C9H6BrNOS2
Molecular Weight	288.18 g/mol
Synonyms	8-Bromobenzo[C]thieno[2,1-E]isothiazole 4-oxide, tetrahydro-; 8-Bromo-1,2,3,9b-tetrahydro-5-thia-1,2-diaza-cyclopenta[a]naphthalene 4-oxide; 8-Bromo-1,2,3,9b-tetrahydrobenzo[4,5]thieno[2,1-e]isothiazole 4-oxide; BTTIO; 8-Br-BTTIO; 2169310-95-4
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,9B-tetrahydrobenzo[C]thieno[2,1-E]isothiazole 4-oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.