Description

{2-Oxabicyclo[2.2.2]Octan-4-Yl}Methanol is a specialized bicyclic ether alcohol building block of significant interest in advanced organic synthesis. This compound matters for its unique bridged oxabicyclic structure, which imparts specific stereochemical and conformational properties valuable for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as medicinal chemistry, ligand design, and the synthesis of novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where its rigid bicyclic framework can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chelating ligands in asymmetric catalysis and transition metal complexes, enabling more efficient and selective chemical transformations.
• Polymer & Material Science: Incorporated as a monomer or cross-linking agent to develop specialty polymers with tailored thermal, mechanical, or optical properties.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex odorants and flavoring agents that require specific, constrained molecular shapes.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-opening reactions and functional group transformations.

Basic Information

Product Name	{2-Oxabicyclo[2.2.2]Octan-4-Yl}Methanol
CAS No.	2168235-11-6
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	4-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octane; 2-Oxabicyclo[2.2.2]octane-4-methanol; (2-Oxabicyclo[2.2.2]oct-4-yl)methanol; Bicyclo[2.2.2]oct-5-ene-2-methanol, 1,3,3-trimethyl-; Endo-Bicyclo[2.2.2]oct-5-ene-2-methanol; 4-Methanol-2-oxabicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our {2-Oxabicyclo[2.2.2]Octan-4-Yl}Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.