Description

Bicyclo[3.2.0]Hept-3-Ene-6-Acetic Acid, 6-(Aminomethyl)-3-Ethyl-, (1S,5R,6S)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate (API intermediate) with a complex bicyclic structure. This compound is valued for its role as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities (NCEs) and complex generics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of proprietary drug candidates, especially those targeting the central nervous system (CNS) or infectious diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Asymmetric Synthesis: Acts as a starting material or intermediate for constructing complex molecules with high enantiomeric purity.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and synthetic chemistry.

Basic Information

Item	Details
Product Name	Bicyclo[3.2.0]Hept-3-Ene-6-Acetic Acid, 6-(Aminomethyl)-3-Ethyl-, (1S,5R,6S)-
CAS No.	2165847-73-2
Molecular Formula	C12H19NO2
Molecular Weight	209.29 g/mol
Synonyms	(1S,5R,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-ene-6-acetic acid; (1S,5R,6S)-3-Ethyl-6-(aminomethyl)bicyclo[3.2.0]hept-3-ene-6-acetic acid; Bicyclo[3.2.0]hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, (1S,5R,6S)-; 2165847-73-2; API Intermediate 2165847-73-2; Chiral Bicyclic Intermediate
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.0]Hept-3-Ene-6-Acetic Acid, 6-(Aminomethyl)-3-Ethyl-, (1S,5R,6S)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry conditions or an inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.