Description

(1,2,3,4-Tetrahydroisoquinolin-6-Yl)Methanol Hydrochloride is a high-purity organic salt derivative of the tetrahydroisoquinoline scaffold, a privileged structure in medicinal chemistry. This compound serves as a critical pharmaceutical intermediate and building block for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, cardiovascular drugs, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Essential building block for constructing compound libraries and exploring structure-activity relationships (SAR) around the tetrahydroisoquinoline core.
• Chemical Synthesis: Used in the development of alkaloid analogs and complex heterocyclic compounds for biological screening.
• Academic & R&D: Serves as a reference standard and starting material in university and contract research organization (CRO) laboratories.
• Process Development: Employed in route scouting and scale-up studies for active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	(1,2,3,4-Tetrahydroisoquinolin-6-Yl)Methanol Hydrochloride
CAS No.	2152637-00-6
Molecular Formula	C10H14ClNO
Molecular Weight	199.68 g/mol
Synonyms	6-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6-isoquinolinemethanol hydrochloride; (6-Tetrahydroisoquinolinyl)methanol hydrochloride; THIQ-6-CH2OH HCl; 6-Hydroxymethyl-THIQ HCl; 1,2,3,4-Tetrahydroisoquinoline-6-methanol hydrochloride
EINECS	Contact for details

Quality Control

Our (1,2,3,4-Tetrahydroisoquinolin-6-Yl)Methanol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.