Description

6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study biological pathways and validate novel drug targets.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological studies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and APIs.

Basic Information

Product Name	6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride
CAS No.	2140866-96-0
Molecular Formula	C14H17N2•2HCl
Molecular Weight	285.22 g/mol (Free base: 213.30 g/mol)
Synonyms	6-(4-Piperidyl)isoquinoline dihydrochloride; 6-(Piperidin-4-yl)isoquinoline hydrochloride (1:2); 6-(Piperidin-4-yl)isoquinoline, 2HCl; 6-(4-Piperidinyl)isoquinoline dihydrochloride; Isoquinoline, 6-(4-piperidinyl)-, dihydrochloride; 2140866-96-0; 6-Piperidin-4-yl-isoquinoline dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.