Description

(2R)-1-Chloro-3-(1H-indol-4-yloxy)propan-2-ol is a chiral, functionalized propanol derivative containing both an indole ether and a chlorohydrin moiety. This compound is of significant value as a sophisticated pharmaceutical intermediate or research chemical for the synthesis of biologically active molecules. It is primarily needed by R&D organizations and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the biological activity of novel indole-containing compounds.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function or protein interactions.
• Asymmetric Synthesis: Utilized in the development of new catalytic or stoichiometric asymmetric methodologies due to its defined stereochemistry.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	(2R)-1-Chloro-3-(1H-indol-4-yloxy)propan-2-ol
CAS No.	2132997-35-2
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	2-Propanol, 1-chloro-3-(1H-indol-4-yloxy)-, (2R)-; (R)-1-Chloro-3-(1H-indol-4-yloxy)propan-2-ol; (2R)-1-Chloro-3-(1H-indol-4-yloxy)-2-propanol; (R)-1-Chloro-3-(1H-indol-4-yloxy)-2-propanol; 4-[(2R)-1-Chloro-2-hydroxypropoxy]-1H-indole; (2R)-1-Chloro-3-(indol-4-yloxy)propan-2-ol; CAS 2132997-35-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.