Description

tert-Butyl 2-Methyl-2-(5-Methyl-6-(Oxazol-2-Yl)-2,4-Dioxo-1,2-Dihydrothieno[2,3-D]Pyrimidin-3(4H)-Yl)Propanoate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in oncology and antiviral research. Its precise molecular architecture offers a strategic handle for further chemical modifications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Oncology Drug Development: A potential scaffold for creating compounds that inhibit specific enzymes or protein-protein interactions involved in cancer progression.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral medications due to its heterocyclic core.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study and modulate biological processes at a molecular level.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-Methyl-2-(5-Methyl-6-(Oxazol-2-Yl)-2,4-Dioxo-1,2-Dihydrothieno[2,3-D]Pyrimidin-3(4H)-Yl)Propanoate
CAS No.	2131091-31-9
Molecular Formula	C20H23N3O5S
Molecular Weight	417.48 g/mol
Synonyms	tert-Butyl 2-methyl-2-(5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-3-yl)propanoate; 3-(2-tert-Butoxy-1,1-dimethyl-2-oxoethyl)-5-methyl-6-(1,3-oxazol-2-yl)-1H-thieno[2,3-d]pyrimidine-2,4(3H)-dione; 2,4-Dioxo-1,2-dihydrothieno[2,3-d]pyrimidin-3(4H)-yl)propanoic acid tert-butyl ester derivative; CAS 2131091-31-9; Thienopyrimidinedione oxazole derivative; Advanced heterocyclic intermediate; Pharmaceutical building block 2131091-31-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-2-(5-Methyl-6-(Oxazol-2-Yl)-2,4-Dioxo-1,2-Dihydrothieno[2,3-D]Pyrimidin-3(4H)-Yl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.