Description

5-Chloro-6-(Morpholino)Pyridine-3-Boronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its pyridine-morpholine scaffold for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and functionalized polymers.
• Chemical Biology & Probe Development: Useful for constructing molecular probes and bioconjugates due to the reactivity of the boronic acid group.
• Academic & Contract Research: Serves as a versatile reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and library synthesis.

Basic Information

Product Name	5-Chloro-6-(Morpholino)Pyridine-3-Boronic Acid
CAS No.	2130896-19-2
Molecular Formula	C9H12BClN2O3
Molecular Weight	242.47 g/mol
Synonyms	5-Chloro-6-morpholinopyridine-3-boronic acid; (5-Chloro-6-morpholinopyridin-3-yl)boronic acid; 3-Borono-5-chloro-6-morpholinopyridine; 5-Chloro-6-morpholino-3-pyridineboronic acid; 2130896-19-2; 5-Chloro-6-morpholin-4-ylpyridine-3-boronic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Morpholino)Pyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for research and non-GMP kilo-lab scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.