Description

n-Mal-n-Bis(Peg2-Amine) Tfa Salt is a specialized bifunctional PEGylated amine derivative, presented as its trifluoroacetate salt for enhanced stability and handling. This compound is a critical intermediate for the synthesis of advanced bioconjugates, offering controlled spacing and solubility for linking bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel drug delivery systems, diagnostic agents, and next-generation therapeutics.

Application

• Bioconjugation Linker: Serves as a versatile spacer and linker for attaching peptides, proteins, oligonucleotides, or small molecule drugs to carriers like antibodies, nanoparticles, or polymers.
• Drug Delivery System Development: Used in the design and synthesis of prodrugs and targeted delivery platforms, leveraging its PEG chains for improved pharmacokinetics and reduced immunogenicity.
• Diagnostic Probe Synthesis: A key building block for creating fluorescent, radioactive, or other labeled probes for imaging and diagnostic applications.
• Hydrogel and Biomaterial Fabrication: Employed as a cross-linking agent or functional monomer in the creation of biocompatible hydrogels and scaffolds for tissue engineering.
• Surface Functionalization: Used to modify surfaces (e.g., chips, sensors, beads) with amine-reactive groups for subsequent biomolecule immobilization.
• Antibody-Drug Conjugate (ADC) Research: A valuable intermediate in the research and development of novel ADC constructs.

Basic Information

Product Name	n-Mal-n-Bis(Peg2-Amine) Tfa Salt
CAS No.	2128735-20-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N,N-Bis(2-(2-aminoethoxy)ethyl)malonamide Trifluoroacetate Salt; Mal-PEG2-Amine (Bis) TFA Salt; 1,1'-(Malonyl)bis[N-(2-(2-aminoethoxy)ethyl)]-2,2,2-trifluoroacetamide; Bis(PEG2-amine) Malonamide TFA Salt; Bifunctional PEG2 Amine Malonamide TFA Salt; Malonyl-bis-PEG2-amine TFA; PEG2 Diamine Malonamide Derivative TFA Salt
EINECS	Contact for details

Quality Control

Every batch of n-Mal-n-Bis(Peg2-Amine) Tfa Salt is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.