Description

3-Hydroxy-2-Methoxybenzeneboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining a key reagent for Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted biphenyl or phenyl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a scaffold in medicinal chemistry for probing biological targets.
• Chemical Biology & Diagnostics: Utilized in the synthesis of molecular probes, sensors, and tags for biochemical research and diagnostic applications.

Basic Information

Product Name	3-Hydroxy-2-Methoxybenzeneboronic Acid, Pinacol Ester
CAS No.	2121514-31-4
Molecular Formula	C13H19BO4
Molecular Weight	250.10 g/mol
Synonyms	2-Methoxy-3-hydroxyphenylboronic acid pinacol ester; (2-Methoxy-3-hydroxyphenyl)boronic acid pinacol ester; 3-Hydroxy-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-3-hydroxybenzeneboronic acid pinacol ester; Boronic acid, B-(2-methoxy-3-hydroxyphenyl)-, 1,1-dimethylethyl ester; 5,5-Dimethyl-2-(2-methoxy-3-hydroxyphenyl)-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Methoxybenzeneboronic Acid, Pinacol Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.