Description

2-Methoxy-3-(n-Methansulfonamide)Pyridine-5-Boronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its boronic acid functionality for structure-activity relationship (SAR) studies.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, where the pyridine and boronic acid groups offer tunable properties.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes, inhibitors, and activity-based protein profiling (ABPP) reagents.
• Catalyst & Ligand Synthesis: Serves as a starting material for creating novel bidentate or tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific, high-value boronic acid derivatives.

Basic Information

Product Name	2-Methoxy-3-(n-Methansulfonamide)Pyridine-5-Boronic Acid
CAS No.	2121513-41-3
Molecular Formula	C7H11BN2O5S
Molecular Weight	246.05 g/mol
Synonyms	(5-Borono-2-methoxypyridin-3-yl)methanesulfonamide; 2-Methoxy-3-(methylsulfonamido)pyridine-5-boronic acid; 3-(Methanesulfonamido)-2-methoxypyridine-5-boronic acid; 5-Borono-2-methoxy-N-(methylsulfonyl)pyridin-3-amine; 2-Methoxy-3-(N-methanesulfonylamino)pyridine-5-boronic acid; Boronic acid, B-[3-[(methylsulfonyl)amino]-2-methoxy-5-pyridinyl]-; CAS 2121513-41-3
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-3-(n-Methansulfonamide)Pyridine-5-Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.