Description

Fenretinide-D4 is a deuterated analog of the synthetic retinoid Fenretinide, specifically designed for use as an internal standard in quantitative analytical methods. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of pharmacokinetic and metabolic studies. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require precise measurement of Fenretinide in complex biological matrices.

Application

• Internal Standard for LC-MS/MS Analysis: Primary application for the accurate quantification of Fenretinide in bioanalytical studies.
• Pharmacokinetic (PK) and Toxicokinetic (TK) Studies: Used to track drug absorption, distribution, metabolism, and excretion (ADME) with high precision.
• Metabolite Identification and Profiling: Aids in distinguishing drug-derived metabolites from endogenous compounds in mass spectrometry.
• Method Development and Validation: Serves as a critical component in establishing robust, regulatory-compliant analytical methods for GLP and clinical studies.
• Drug Metabolism Research: Facilitates research into the metabolic pathways and stability of retinoid-based therapeutics.
• Quality Control in Pharmaceutical Manufacturing: Can be employed in process control and stability testing of Fenretinide drug substances and products.

Basic Information

Item	Detail
Product Name	Fenretinide-D4
CAS No.	2118244-64-5
Molecular Formula	C26H28D4O2
Molecular Weight	~ 392.58 g/mol
Synonyms	N-(4-Hydroxyphenyl)retinamide-d4; 4-HPR-d4; Fenretinide (phenyl-d4); [D4]-Fenretinide; All-trans-N-(4-hydroxyphenyl)retinamide-d4; 4-Hydroxyphenylretinamide-d4; NSC 374551-d4; LGD1069-d4
EINECS	Contact for details

Quality Control

Every batch of Fenretinide-D4 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A Certificate of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and solvent content is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.