Description

Ethyl 6-Methylsulfonyl-1H-Indole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct indole core functionalized with a methylsulfonyl group and an ethyl ester. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in the development of chemical probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex, functionalized indole derivatives for various high-value applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and novel heterocyclic chemistry.

Basic Information

Product Name	Ethyl 6-Methylsulfonyl-1H-Indole-2-Carboxylate
CAS No.	2107567-93-9
Molecular Formula	C₁₂H₁₃NO₄S
Molecular Weight	267.30 g/mol
Synonyms	6-(Methylsulfonyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-(methylsulfonyl)-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 6-(methylsulfonyl)-, ethyl ester; Ethyl 6-methanesulfonyl-1H-indole-2-carboxylate; 2107567-93-9; 6-Methylsulfonylindole-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Methylsulfonyl-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.