Description

tert-Butyl 7-Fluoro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate (Wxc07248) is a high-purity, advanced pharmaceutical intermediate belonging to the dihydroisoquinoline class of compounds. This molecule is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is essential for research and development chemists, process scale-up engineers, and manufacturers in the global pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development and commercial production of novel drug candidates, especially those with a dihydroisoquinoline core structure.
• CNS Drug Synthesis: Used in the research and manufacturing of potential therapeutics for neurological and psychiatric conditions.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development of robust, cost-effective, and scalable synthetic pathways from laboratory to pilot plant and commercial production.
• Fine Chemical Synthesis: Utilized as a specialized building block for creating complex fluorinated organic molecules in custom synthesis projects.
• Contract Manufacturing (CMO/CDMO): A critical raw material for contract manufacturing organizations serving the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 7-Fluoro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate (Wxc07248)
CAS No.	2102412-01-9
Molecular Formula	C14H16FNO2
Molecular Weight	249.28 g/mol
Synonyms	7-Fluoro-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; tert-Butyl 7-fluoro-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; 2-Boc-7-fluoro-1,2,3,4-tetrahydroisoquinoline; 7-Fluoro-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester; WXC07248; BOC-7-Fluoro-THIQ; 2102412-01-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Fluoro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.