Description

Vh032 Thiol CAS NO 2098836-54-3 is a high-purity, specialized thiol compound designed for advanced research and pharmaceutical development. This compound serves as a critical building block and reactive intermediate in the synthesis of complex molecules, particularly in the field of targeted protein degradation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for innovative drug discovery programs.

Application

• Proteolysis-Targeting Chimera (PROTAC) Development: A key component in the synthesis of PROTAC molecules, which are a revolutionary class of therapeutics.
• Bioconjugation and Linker Chemistry: Used for site-specific conjugation of payloads to antibodies, proteins, or other biomolecules.
• Pharmaceutical Intermediate: Serves as a crucial synthetic intermediate in the production of active pharmaceutical ingredients (APIs).
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and cellular signaling pathways.
• Material Science: Potential use in modifying surface properties of polymers and nanomaterials through thiol-based reactions.
• Peptide and Protein Modification: Facilitates the introduction of specific functional groups into peptides for enhanced stability or activity.

Basic Information

Product Name	Vh032 Thiol
CAS No.	2098836-54-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VH032 Thiol; VH032-Thiol; VH032 Thiol derivative; (S,R,S)-AHPC-PEG2-VH032 thiol; VHL Ligand VH032 thiol; E3 ligase ligand VH032 thiol; VH032-based PROTAC linker; VHL-recruiting thiol
EINECS	Contact for details

Quality Control

Our Vh032 Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.